Varsha Gandhi Selected Research

9-arabinofuranosylguanine

1/2017	Nelarabine in the treatment of pediatric and adult patients with T-cell acute lymphoblastic leukemia and lymphoma.
3/2008	Phase I trial of nelarabine in indolent leukemias.
6/2002	Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase.

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Varsha Gandhi Research Topics

Disease

56	Neoplasms (Cancer) 01/2022 - 01/2002
56	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 09/2005
26	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 03/2022 - 02/2002
26	Leukemia 10/2018 - 02/2002
20	Multiple Myeloma 06/2017 - 08/2002
16	Hematologic Neoplasms (Hematological Malignancy) 01/2020 - 12/2003
9	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2021 - 11/2009
9	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2017 - 06/2002
8	Lymphoma (Lymphomas) 01/2017 - 01/2002
8	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 11/2014 - 10/2003
6	B-Cell Lymphoma (Lymphoma, B Cell) 01/2021 - 10/2005
6	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 08/2012 - 10/2003
5	Disease Progression 01/2022 - 02/2012
5	Purine Nucleoside Phosphorylase Deficiency 01/2017 - 12/2005
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 01/2013
4	Breast Neoplasms (Breast Cancer) 10/2018 - 06/2010
3	Lymphopenia (Lymphocytopenia) 08/2013 - 12/2007
2	Residual Neoplasm 01/2021 - 03/2011
2	Diarrhea 01/2018 - 06/2014
2	Exanthema (Rash) 01/2018 - 11/2017
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2017 - 08/2013
2	Blast Crisis (Blast Phase) 08/2012 - 02/2005
2	T-Lymphocytopenia 10/2006 - 12/2005
1	Infections 01/2021

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2002
20	NucleosidesIBA 01/2022 - 08/2002
20	Phosphotransferases (Kinase)IBA 07/2021 - 06/2002
20	Clofarabine (Clolar)FDA Link 01/2018 - 03/2003
15	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2018 - 10/2002
14	ibrutinibIBA 01/2022 - 02/2012
11	fludarabineIBA 12/2021 - 01/2002
10	venetoclaxIBA 03/2022 - 08/2015
10	triphosphoric acid (triphosphate)IBA 03/2010 - 06/2002
9	DNA (Deoxyribonucleic Acid)IBA 06/2017 - 01/2002
8	Purine-Nucleoside PhosphorylaseIBA 01/2017 - 12/2005
8	RNA (Ribonucleic Acid)IBA 01/2017 - 11/2003
7	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 02/2012
7	Adenosine Triphosphate (ATP)IBA 01/2022 - 06/2005
7	Biological ProductsIBA 04/2019 - 08/2010
6	Pharmaceutical PreparationsIBA 10/2018 - 09/2003
6	ProdrugsIBA 01/2018 - 05/2002
6	proto-oncogene proteins pimIBA 01/2018 - 11/2009
6	forodesineIBA 08/2013 - 12/2005
5	Bendamustine Hydrochloride FDA Link 03/2017 - 08/2002
5	8-chloroadenosineIBA 01/2015 - 09/2009
5	SGI 1776IBA 09/2013 - 11/2009
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2021 - 09/2007
4	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2018 - 12/2011
4	Purine NucleosidesIBA 01/2018 - 04/2005
4	Arabinofuranosylcytosine TriphosphateIBA 01/2018 - 10/2002
4	idelalisibIBA 03/2017 - 04/2015
4	nelarabine (506U78)FDA Link 01/2017 - 06/2002
4	Adenosine (Adenocard)FDA LinkGeneric 01/2015 - 06/2005
4	Messenger RNA (mRNA)IBA 09/2013 - 06/2005
4	deoxyguanosine triphosphate (dGTP)IBA 08/2013 - 12/2003
3	Rituximab (Mabthera)FDA Link 12/2021 - 04/2015
3	AZD1208IBA 04/2019 - 12/2016
3	GuanosineIBA 01/2017 - 09/2003
3	9-arabinofuranosylguanineIBA 01/2017 - 06/2002
3	Apoptosis Regulatory ProteinsIBA 01/2017 - 01/2016
3	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 04/2014 - 12/2003
3	Tyrosine (L-Tyrosine)FDA Link 09/2013 - 07/2009
3	Cladribine FDA LinkGeneric 07/2006 - 10/2002
3	Gemcitabine FDA Link 08/2004 - 02/2002
2	NucleotidesIBA 01/2022 - 03/2009
2	tapotoclaxIBA 01/2022 - 01/2020
2	Protein Kinases (Protein Kinase)IBA 01/2021 - 04/2012
2	EstersIBA 10/2018 - 07/2012
2	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2018 - 11/2017
2	Transaminases (Aminotransferases)IBA 11/2017 - 06/2014
2	ARQ 197IBA 06/2017 - 03/2015
2	duvelisibIBA 05/2017 - 01/2017
2	Protein Isoforms (Isoforms)IBA 05/2017 - 12/2006
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 01/2013
2	Ursolic AcidIBA 11/2016 - 11/2016
2	carfilzomibIBA 09/2016 - 01/2015
2	Caspase 3 (Caspase-3)IBA 01/2016 - 11/2015
2	pyrimidineIBA 08/2015 - 11/2002
2	bcr-abl Fusion ProteinsIBA 04/2014 - 11/2006
2	Threonine (L-Threonine)FDA Link 09/2013 - 10/2012
2	Serine (L-Serine)FDA Link 09/2013 - 10/2012
2	8-aminoadenosineIBA 12/2010 - 03/2010
2	N- (5- (((5- (1,1- dimethylethyl)- 2- oxazolyl)methyl)thio)- 2- thiazolyl)- 4- piperidinecarboxamideIBA 08/2010 - 05/2009
2	purineIBA 08/2010 - 11/2003
2	EnzymesIBA 08/2010 - 12/2005
2	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 03/2009 - 12/2006
2	9-beta-D-arabinofuranosylguanosine 5'-triphosphateIBA 03/2008 - 06/2002
1	Lenalidomide (CC 5013)FDA Link 01/2022
1	Chimeric Antigen ReceptorsIBA 01/2022
1	vecabrutinibIBA 01/2022
1	pirtobrutinibIBA 01/2022
1	NADP (NADPH)IBA 01/2022
1	obinutuzumabIBA 12/2021
1	ZinostatinIBA 01/2021
1	IonophoresIBA 01/2021
1	Cysteine (L-Cysteine)FDA Link 01/2021
1	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone (FCCP)IBA 01/2021

Therapy/Procedure

26	Therapeutics 01/2022 - 02/2002
6	Drug Therapy (Chemotherapy) 02/2019 - 12/2011
2	Intravenous Infusions 02/2005 - 12/2003